Since time immemorial, humankind has wondered about its origins and the meaning of life. Are we really alone in the universe? Why do poverty, injustice, war, and death exist? Is there really a higher power that governs everything? It is difficult to find answers to these questions in a world dominated by relativism, where adherents of a thousand different belief systems each claim to possess the truth. There is, nevertheless, a science that can guide our quest for absolute knowledge, and it is into this science that the pivotal, though largely unknown text, Shri Ishopanishad, initiates us. Masters of this primordial wisdom have been delivering it since the world began, but only the most sincere souls know how to take advantage of it. Are we up to the task?